Karaoke for pianists: silence the tune in the file, keep the rest of the arrangement playing, and perform the melody over it. With a MIDI keyboard connected, the on-screen keys show what you play as you play it.
What you need
A song where the melody has its own track. If the melody and chords share one piano track, split it first (see Split a piano track into two hands) and treat the Right Hand track as the melody.